Research Shows that HBOT Heals Sores, Injuries and Non-healing Wounds


Numerous studies have documented the benefits of hyperbaric oxygen therapy (HBOT) for healing diabetic wounds and delayed radiation injuries.

HBOT supports healing by increasing neovascularization by angiogenesis (growth of new blood vessels from endothelial cells) and vasculogenesis (recruitment and differentiation of the wound bed of circulating stem and progenitor cells). HBOT is also bacterioststic and bactericidal, improves post-ischemic tissue survival, and improves chronic osteonecrosis.

HBOT has also been shown to help heal a wide range of additional injuries that are also characterized by low oxygen and low blood flow, such as compromised flaps and grafts, osteomyelitis and burns.

When oxygen tensions are elevated, the initial effects of increased production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) result in:

Improved neovascularization with Increased wound growth factor synthesis∘ SPCs mobilization from bone marrow Improved post-ischemic tissue survival - Neutrophil B-actin s-nitrosylation Lower monocyte chemokine synthesis Ischemic preconditioning changes HO-1, HSPs, HIF-1 Ischemic preconditioning changes HO-1, HSPs, HIF-1

We have worked with hundreds of physician-refered patients with non-healing wounds that are a result of diabetes or delayed radiation injury.

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How Hyperbarics Helps

  • Increases blood flow and oxygenation
  • Stimulates tissue repair
  • Induces stem cell reproduction and mobilization
  • Stimulates up-regulation of growth hormones
  • Prevents amputations

What the Research Says

Several studies highlight benefits of HBOT in healing radiation damage to
the chest and breast:


  1. Delayed Radiation Injury
  2. Clinical Effectiveness
  3. Coll Clin Wound
    J Am Coll Clin Wound Spec. 2014 Apr; 6(1-2): 9–13.
  4. Chronic wound
  5. Enoch Huang
    29 May 2019 Volume 2019:6 Pages 27—37 Dove Press

Patient Experiences

  • George

    David, 64

    A wound on his leg, with a skin graft, would not heal. After HBOT, the wound closed.
    David, a retired software project manager, had a 100% arterial occlusion for which he received an arterial stint. When a 2 1/2 inch diameter wound on his right leg with a graft wouldn’t heal, he came to HBOT. After receiving his prescribed HBOT sessions, the wound closed, and he was able to resume his typical activities. Continue reading
  • Amita-22-Pic

    Amita, 22

    Gangrene on her foot would not heal. HBOT prevented amputation.
    Amita was an active hiker, but because of gangrene, lost all the toes on her right foot. Unfortunately, the surgical wound from the amputation would not heal , and her doctors were planning to amputate her foot.After a series of HBOT sessions, her wound healed up. A year later when we checked in with Amita, the wound was still healed. Continue reading
  • Howard-1

    John, 72

    Had skin grafts that had trouble healing. HBOT helped the threatened grafts heal.
    John had compartment syndrome and infections after having received multiple surgeries over 6 months. He also had a failed graft. John’s doctor sent him to HBOT to prepare him for a new graft, which was successful. After applying the new graft, John’s doctor sent him back to HBOT to help the new (threatened) graft heal. In the end, John’s grafts all healed. Continue reading

Refer a Patient


Refer a Patient

You submit patient’s information

As a provider, your office fills out and faxes back the Patient Referral Form. Have questions? Call us!

We get authorizations

We make sure the patient understands treatment and then follow the prescribed protocol to get the patient on the road to recovery!

Patient starts HBOT

Our medical staff meets with the patient to ensure that HBOT is appropriatre, and contacts Medicare or private insurance to receive authorization.

Research on Hyperbaric Therapy

To learn more about HBOT, take a look at our FAQs.


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  • What is Hyperbaric Medicine?

    Hyperbaric medicine, also called hyperbaric oxygen therapy or HBOT, is a medical treatment where a patient sits or lies in pressurized chamber and breathes 100% oxygen. In HBOT, oxygen dissolves into the blood, thus raising the oxygen concentration to very high levels.This increased oxygen is a primary building block for tissues, muscle, and bone repair. Among other benefits, it kicks off cell reproduction, heals injuries and infection more rapidly, and decreases inflammation.

  • Can HBOT help Neuropathy?

    Hyperbaric treatments help heal neuropathy by regrowing small blood vessels and nerves that have died from disease, injuries from radiation and aging. Patients often experience numbness and or pain when they start treatment. Hyperbaric treatments most often bring back sensation and make, for example, walking easier and more enjoyable.

  • Does HBOT kill cancer cells?

    Current research indicates that hyperbaric oxygen does not kill cancer cells. However, there has been a small amount of research indicating that hyperbaric oxygen might reduce the size of certain tumors. Also, there has been a study on mice using hyperbaric oxygen, along with a ketogenic diet, to reduce tumors. Hyperbaric oxygen causes many different healing modalities to kick into gear. Could its effect on strengthening the immune system inhibit the growth of cancer cells? Nobody knows. There are numerous studies conclusively showing that hyperbaric oxygen does not encourage cancer cells or tumors to grow. Some patients claim the hyperbaric oxygen makes them feel a lot more comfortable and functional after chemotherapy and also during healing. Note that some chemotherapy drugs are not to be used with hyperbaric oxygen, as the chemotherapy drugs can be enhanced and thus become toxic. A good hyperbaric oxygen facility (such as Bay Area Hyperbarics) will always call the chemotherapy manufacturer to ensure that hyperbaric oxygen therapy will be helpful and not damaging to the patient.

  • Why would a physician consider HBOT?

    A physician would consider using hyperbaric chamber therapy under a variety of situations. Physicians most typically refer patients to hyperbarics when the patient is not healing with traditional medical interventions and hyperbaric chamber therapy is approved by Medicare for this condition.

    Some patients experience significant unresolved pain and unremitting disease states that the mechanisms of hyperbaric oxygen therapy in a hyperbaric chamber are known to affect, such as the down regulation of inflamatory genes. For an example, some patients have experienced severe, unremitting hives with itching, which did not improve with any specialists interventions.

    Some physicians will consider hyperbaric chamber therapy if the patient has no other good avenues for improving their failing health, and they know the hyperbaric chamber therapy is safe and will not harm the patient.

  • What is the CPT code for HBOT?

    The CPT code for HBOT is G0277.

  • What is Hypebaric Oxygen Therapy?

    Hyperbaric Oxygen Therapy (HBOT) Hyperbaric Oxygen Therapy (HB0T) is a medical treatment where you inhale 100% oxygen in a chamber with increased atmospheric pressure. HBOT injects 400x the oxygen into your tissues and bones and mobilizes stem cells. It regrows healthy tissues in the brain, blood vessels, skin and bones. It also reduces pain and swelling, and speeds recovery.

    It is simple, effective and painless.

  • Does Medicare cover HBOT?

    Medicare covers Hyperbaric Oxygen Therapy for approved conditions, and many insurance companies also cover approved conditions. If your condition is not approved by your insurance, we can discuss our special rates. Give us a call at (408) 356–7438. We are happy to discuss your options with you.