The Role of HBOT Treatment in Chronic Pain Relief

By Lisa St. John, M.S.
The Role of HBOT Treatment in Chronic Pain Relief

Learn about the impact of chronic pain on physical and mental health. Discover how HBOT treatment helps with chronic pain relief with Bay Area Hyperbarics.

Chronic pain is a debilitating condition affecting millions across the United States. It can manifest in various forms and intensities, often leading to a diminished quality of life. In recent years, Hyperbaric Oxygen Therapy (HBOT) has emerged as a promising option for chronic pain management.

HBOT involves breathing pure oxygen in a pressurized chamber. The increased pressure enables the blood to carry more oxygen, which it delivers to the body's tissues. In this blog, we'll explore chronic pain, its impact on physical and mental health, and how HBOT can relieve those suffering from it.

What Is Chronic Pain?

Chronic pain is pain that persists for longer than 12 weeks. Unlike acute pain, usually linked to an injury or an underlying medical condition that eventually heals, chronic pain persists long after the initial cause has resolved. Chronic pain can last for weeks, months, or even years. It can affect various body parts, including the back, joints, muscles, and nerves. 

A variety of factors can cause chronic pain, including:

  • Injury: This can include fractures, sprains, strains, and soft tissue injuries.
  • Illness: This can include arthritis, cancer, diabetes, and neurological disorders.
  • Disease: This can include fibromyalgia, migraines, and complex regional pain syndrome (CRPS).

Impact of Chronic Pain on Physical and Mental Health

Chronic pain goes beyond the physical discomfort it inflicts. It takes a significant toll on an individual's mental and emotional well-being. The constant presence of pain can lead to frustration, anxiety, depression, and a reduced ability to perform daily activities. It can also disrupt sleep patterns, exacerbating the overall burden on one's health.

How Hyperbaric Oxygen Therapy Works for Chronic Pain

Hyperbaric Oxygen Therapy is a medical treatment that involves breathing pure oxygen in a pressurized chamber. The increased pressure helps the lungs absorb more oxygen, aiding in the treatment of chronic pain in various ways, including:

  • Increased oxygen delivery. HBOT increases the amount of oxygen that the blood can carry. The body delivers this extra oxygen to its tissues, which can help reduce inflammation and promote healing.
  • Reduced inflammation. Inflammation is a common cause of chronic pain. HBOT can help to reduce inflammation by increasing the production of anti-inflammatory substances.
  • Stimulation of angiogenesis. Angiogenesis is the process of new blood vessel formation. HBOT can stimulate angiogenesis, which can help to improve blood flow to the affected areas and promote healing.
  • Reduction of nerve sensitivity. HBOT can help to reduce the sensitivity of nerve endings, which can lead to a reduction in pain.

The Impact of Oxygen Therapy on the Nervous System and Pain Receptors

HBOT can positively affect the central nervous system and pain receptors. These include:

  1. HBOT can help to reduce inflammation in the nervous system, which can lead to a reduction in pain.
  2. Hyperbarics can help promote the growth and regeneration of nerve cells, improving nerve function and reducing pain.
  3. Hyperbaric oxygen also regrows new blood vessels and improves blood flow.
  4. HBOT down-regulates over 4,000 inflammatory genes.
  5. Hyperbaric treatment helps build new neurons.

Chronic Pain Conditions Treated With HBOT

Hyperbaric Oxygen Therapy can help treat a variety of chronic pain conditions, including but not limited to:


Arthritis, characterized by inflammation and joint pain, often responds well to HBOT. The increased oxygenation dramatically reduces inflammation and alleviates pain associated with this condition. 

Complex Regional Pain Syndrome (CRPS)

CRPS is a chronic and debilitating condition that affects the limbs, causing severe pain and impaired mobility. HBOT mitigates the symptoms and improves the quality of life for CRPS patients.

Concussion, Traumatic Brain Injury (TBI), and Anoxic Brain Injuries

HBOT has been explored as a potential therapy for individuals recovering from brain injuries. Research shows that HBOT significantly helps heal the brain after traumatic brain injury. The oxygen-under-pressure in hypberbarics can aid in:

  • Suppressing inflammation
  • Increasing tissue oxygenation
  • Inhibiting neuronal death
  • Activating idling neurons
  • Creating synapses
  • Decreasing cerebral edema
  • Stimulating stem cell production and mobilization


Fibromyalgia causes widespread pain, fatigue, and tender points throughout the body. HBOT has shown promise in reducing pain intensity and improving the overall well-being of fibromyalgia patients. In recent studies, up to 70% of fibromyalgia patients who received hyperbaric oxygen therapy no longer met the medical criteria of someone with fibromyalgia. Some of the effects of HBOT in fibromyalgia patients include:

  • Stimulates neuroplasticity and rectifies abnormal brain activity in pain-related areas of FMS patients
  • Heals brain lesions and fissures
  • Decreases FMS symptoms
  • Decreases psychological distress

Headaches & Migraines

Chronic headaches and migraines can be debilitating. HBOT has been used to alleviate the intensity and frequency of these painful episodes by:

  • Opening blood vessels to increase blood supply
  • Decreasing inflammation
  • Building new blood vessels
  • Increasing oxygen carried in blood plasma, enabling more oxygen to reach the brain and body

Sports Injuries

Sports-related injuries like muscle strains, ligament tears, and bone fractures can lead to persistent pain. HBOT can aid in the athletic recovery process, helping athletes regain mobility and function. HBOT helps treat chronic pain from sports injuries with:

  • Hyperoxygenation
  • Collagen synthesis
  • Attenuation of reperfusion injury
  • Neovascularization
  • Vasoconstriction
  • Bubble reduction
  • Fibroplasia
  • Increased WBC killing capacity
  • Stem cell mobilization

Benefits of HBOT for Chronic Pain Relief

HBOT can offer several benefits for relieving chronic pain, including:

Reduction of Pain Intensity and Frequency

Many patients report a significant reduction in the intensity and frequency of their chronic pain after undergoing HBOT treatment. This can provide much-needed relief and improved quality of life.

Improvement in Mobility and Functionality

HBOT can enhance mobility and functionality, helping individuals regain the ability to perform daily tasks and engage in physical activities that may have been challenging before. This can also lead to improvements in mood and overall well-being.

Decreased Reliance on Pain Medications

Reducing the reliance on pain medications is a critical aspect of chronic pain management. HBOT can help individuals reduce dependence on medications, which often have side effects and the risk of addiction. Numerous patients have told us that persistent pain simply disappeared for them during and after hyperbarics.

Enhanced Overall Quality of Life

By alleviating chronic pain, HBOT can improve life quality and enable more active and fulfilling lifestyles.This can lead to improved mental health, increased social engagement, and better overall well-being.

Get Started with Hyperbarics for Chronic Pain Relief

Chronic pain is a complex and challenging condition that affects not only physical health but also mental well-being. Hyperbaric Oxygen Therapy has emerged as a promising chronic pain treatment option by addressing the underlying factors contributing to discomfort.

If you or a loved one are dealing with chronic pain and seeking effective relief, consider exploring the benefits of Hyperbaric Oxygen Therapy at Bay Area Hyperbarics in San Jose, CA. Physicians treating chronic pain patients can also refer them to our hyperbaric clinic. Our team is here to answer your questions, provide guidance, and help you take the first steps towards a pain-free future. Contact Bay Area Hyperbarics today to learn more about our HBOT treatment options for pain-related conditions.

Lisa St. John, M.S.
Lisa St. John, M.S.
Clinic Director and Founder

Lisa is our Clinic Director and Founder. She earned her Master’s degree from Harvard University, completed a Fellowship at Stanford University, and has spent the last 30 years working in the healthcare field.

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The Role of HBOT Treatment in Chronic Pain Relief

Learn about the impact of chronic pain on physical and mental health. Discover how HBOT treatment helps with chronic pain relief with Bay Area Hyperbarics.


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